EZH2 and gastric cancer: In gastric cancer, it sequesters miR-34a to upregulate c-Met (MET proto-oncogene, receptor tyrosine kinase) and SNAIL (snail family transcriptional repressor 1) to promote EMT and metastasis; at the same time, it interacts with EZH2 or recruits PRC2 to the promoter of miR-34a to repress its expression [115,116].