A large body of evidence indicates that certain n-3 fatty acids can selectively interfere with the viability of tumor cells, exerting their effects through several mechanisms, such as generation of reactive oxygen species (ROS), lipid peroxidation, activation of caspases and peroxisome proliferator-activated receptors (PPAR), and modulation of oncogenes expression [29,30]. This evidence concerns the gene PPARA and neoplasm.