The effects of pomegranate peel extract (PoPx) on prostate cancer cell lines examined by Deng et al. (2017) demonstrated that PoPx incubation can induce apoptosis by the loss of mitochondrial transmembrane potential (Δym), the increased reactive oxygen species (ROS) as well as the augmented Bax/Bcl-2. This evidence concerns the gene BCL2 and Familial prostate cancer.