GJA1 and breast carcinoma: Cx43 is by far the best studied connexin, and a number of functional microRNAs targeting this gene have been identified, including miR-1, miR-23a, miR-186, miR-200a, miR-206, and miR-381 in human breast cancer [81], miR-20a in human prostate cancer [82], miR-221/222 in glioblastoma multiforme [83], and miR-206, miR-1, and miR-133 in cardiac myocytes and during skeletal myoblast differentiation [84,85,86].