Finally, different studies have proved that CAFs isolated from different cancer types, invasive breast cancer or urinary bladder cancer, secrete TGF-β in their media, which can induce EMT in the adjacent cancer cells in a paracrine manner, by inducing the long non-coding RNA ZEBNAT and the ZEB1 mRNA expression in the case of urinary bladder cancer [113,114]. Here, TGFB1 is linked to urinary bladder cancer.