H19 was once reported to be up‐regulated in plasma from patients with breast cancer;45 however at almost the meantime, another research reported that H19 was not altered in another cohort of patients with breast cancer.46 As to HOTAIR, it was also reported not altered in plasma from patients with GC in Otsuji's research, which was consistent with the current study.41 The inconsistency was not only seen in H19 and HOTAIR, but also in lncRNA MALAT120, 47 and some miRNAs. This evidence concerns the gene HOTAIR and gastric cancer.