A common feature in several neurodegenerative diseases affecting memory is the presence of brain amyloidosis, including plaques (Aβ), tangles (tau) and Lewy bodies (α-synuclein), and neuropathological studies have shown that ADD patients often have other concomitant pathologies, besides plaques and tangles [12, 24, 37]. The gene discussed is MAPT; the disease is neurodegenerative disease.