The low rates of both KRAS and NRAS mutations reported in neoplastic lesions etiologically linked to HPV concurred with the recent results documented for cervical adenocarcinoma.45 Regarding the low prevalence of both BRAF mutations and MSI-high specimens observed in the present study, these latter results are in agreement with those of Yamauchi et al.46 who showed a gradual decrease of these two parameters along the gastrointestinal tract from the ascending colon to the rectum. This evidence concerns the gene NRAS and cervical adenocarcinoma.