KRT7 and neoplasm: The shared expression pattern detected in both normal tissues and invasive cancers further confirms the increasing use of keratin filaments as reliable biomarkers for correlating tumour origin with patient management.30 Moreover, the restricted expression of Krt7 in tumours arising from the anal glands/transitional zone is consistent with prior case reports31–33 and parallels the staining pattern of this biomarker in anal SCC located at the squamocolumnar junction.2,3