To assess EPHB6 effect on TNBC tumours, we injected MDA-pc3 or MDA-B6-M cells into mammary fat pads of NU(NCr)-Foxn1nu (athymic) and NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NOD-SCID) mice (1.5 × 106 cells and 1.5 × 105 cells per animal, respectively). This evidence concerns the gene EPHB6 and neoplasm.