To further explore the angiotensin (Ang)-II contribution in PC-AKI, we assessed gene expression of angiotensinogen (Atgn), angiotensin converting enzymes (Ace) and 2. There was no significant difference in the average gene expression of Atgn, Ace, and Ace-2 levels in the kidneys of contrast treated animals compared to controls at all time points (data not shown). The gene discussed is ACE2; the disease is acute kidney injury.