We found that the frequencies of GATA3+IL-4+, GATA3+IL-5+, and GATA3+IL-13+ CD4+ T-cells in the lungs of asthma-induced Bcl11bfl/fl dLck-iCre mice were reduced, as were the frequencies of GATA3+, IL-4+, IL5+, and IL-13+ CD4+ T-cells. This evidence concerns the gene CD4 and asthma.