AFP and ovarian cancer: The diagnostic tests for ovarian cancer during gestation include pelvic USG, MRI of the abdomen, chest X-ray, CA-125 (despite the fact that levels increase during pregnancy and normalize after 12 weeks gestation), alpha-fetoprotein (AFP), beta-human chorionic gonadotropin, lactase dehydrogenase, liver function tests, urea, creatinine, and intraoperative biopsy also plays a significant role.