Cell‐penetrating VDAC1‐based N‐Ter‐Antp, Tf‐D‐LP4, and Antp‐LP4 peptides and their improved derivatives selectively promoted cancer cell death in over 40 genetically characterized cancer cell lines, derived from different human malignancies, and possessing different pathways for apoptosis evasion (Figs 1, 2, 3 and S1 and Tables 1, 2, 3). This evidence concerns the gene TF and cancer.