Specifically, we found N‐glycan peaks for GP3 (monoantennary monogalactosylated glycan, A1[6]G1), GP30 (tetraantennary tetragalactosylated monosialylated glycan, A4G4S[3]1), GP39 (tetraantennary tetragalactosylated trisialylated glycans, A4G4S3), and GP40 (mostly tetraantennary outerarm fucosylated trigalactosylated trisialylated glycans, A4F1G3S3) to be more abundant in TIF and BC serum samples as compared to NIF and normal serum samples. The gene discussed is PDPN; the disease is breast cancer.