SHARPIN and skin disorder: In summary, we report CerAS(d18:1/24:0)2OH, CerAS(d18:1/16:0)2OH, CerNS(d18:1/16:0), cerotic acid, 16-hydroxy palmitic acid, and docosahexaenoic acid (DHA) as highly discriminative lipids in the dermatitis of SHARPIN-deficient mice.