This patient was erroneously diagnosed in November 2015 with anti-CASPR2 encephalitis, 3 months before the recommendations for a clinical approach to autoimmune encephalitides were published online (1) and 11 months prior to the online publication stating that CASPR2 ab titers (as measured by the Euroimmun assay) in patients diagnosed with autoimmune encephalitis should be much higher than a 1:20 endpoint titer; more specifically, patients with a non-encephalitic MRI (as in this patient) need to have a CASPR2 ab serum titer >1:1,000 to have a >70% likelihood of an autoimmune encephalitis (4). The gene discussed is CNTNAP2; the disease is viral encephalitis.