Both the mRNA and protein expression of MUTYH, a human DNA glycosylase that repairs the foremost oxidative DNA damage in prostate cancer (8-hydroxyguanine), was down-regulated in about two thirds of prostate cancers compared to the non-cancerous prostate tissue data presented in two separate publicly available databases (Shinmura et al., 2017). Here, MUTYH is linked to Familial prostate cancer.