CYP4F2 and cancer: Additionally, the current study identified four SNP associated with objective responses to erlotinib: rs1042640 in UGT1A10, rs1060463, and rs1064796 in CYP4F11 and rs2074900 in CYP4F2. Previous studies have shown that CYP450 family members function in cancer drug metabolism, including in NSCLC.