SMN1 and melanoma: We treated murine melanoma CAFs (mCAFs) or human breast CAFs (hCAFS) with Scriptaid over a 7-day period in the presence or absence of TGFβ (these CAFs were previously isolated and characterised by our laboratories).23,24 We observed that Scriptaid reduced the expression of SMA, fibronectin, col1, and the cytoskeletal protein palladin32 both in the presence and absence of TGFβ (Fig. 2a).