In vitro, VEGF-A165b was found to inhibit the proliferative effect of VEGF-A165a on human primary ECs and ATII cells, with reduced expression of VEGF-A165b in ARDS compared to the normal lung, suggesting a role for VEGF-Axxxb in the repair of the ACM following lung injury [60]. The gene discussed is VEGFA; the disease is acute respiratory distress syndrome.