In 2008, Okumura et al.,(24) published the results of a study about survivin expression, which included 52 cases of pure DCIS and 28 cases of DCIS with foci of microinvasion (DCIS-MI), and showed expression of this protein was significantly higher in the DCIS-MI cases than in those with a sample of only DCIS. Here, BIRC5 is linked to ductal breast carcinoma in situ.