To characterize the cytokine profile associated with DENV infection in rhesus macaques, sera collected before and 1, 4, 6, 8 and 14 days after infection were tested, using a multiplexed microbead-based cytokine assay, for their concentration in soluble IFN-γ, IL-1β, IL-2, IL-6, IL-8, IL-10, IL-12/23, IL-17A, IL-18, MIP-1α, MIP-1ß, TNF-α, TGF-α, VEGF-A and MCP-1. This evidence concerns the gene IL6 and infection.