Therefore, our study aims at first confirming the paracrine effect of MenSCs on neuroprotection and their potential for transdifferentiation into glial-like cells and, subsequently, at examining alterations in the level of N-cad during predifferentiation of MenSCs to explore an alternative source of genetically engineered MenSCs for treating peripheral nerve injury. The gene discussed is CDH2; the disease is peripheral nerve injury.