DNAJB1 and viral infectious disease: Indeed, Hsp90 and DnaJ/HsP40 proteins are not necessarily linked in their role as chaperones to facilitate the folding of diverse client proteins during different biological processes such as virus infection and plant resistance (Li et al., 2012; Verchot, 2012), and the chaperone machinery Hsp90-Sgt1 and Hsp90-Hsp40 is of different partnership for client recruitment and folding (Park and Seo, 2015).