HLA-DPA1*01:03/DPB1*02:01 [for FAAGLFLRKLTSKEL from DENV serotype 2 and HLA-DRB1*11:01 for the other 2 peptides from serotype 3] could suffer from a relatively higher predilection for DHF following infection with DENV serotypes 2 and 3, respectively. This evidence concerns the gene HLA-DPB1 and infection.