This would give pil1 and pil3-carrying SGG an advantage for the adhesion to CRC tissue featuring mislocalized MUC5AC mucin and exposed collagen type IV, the adhesion to fibrinogen at injured sites in the blood system as well as the colonization of collagen type I exposing surfaces such as damaged heart valves (Martins et al., 2016). Here, MUC5AC is linked to colorectal carcinoma.