A heterozygous deletion removing exons 1 to 11 of the GRN gene was reported in an 83 year-old PD patient (Rovelet-Lecrux et al., 2008) and, the IVS0 + 5G>C mutation was reported in a 56 year-old PD patient (Brouwers et al., 2007). The gene discussed is GRN; the disease is Parkinson disease.