ATM is a serine/threonine kinase involving in DNA damage repair, cell arrest and apoptosis, and chromatin remodelling.19, 20 Genetic defects in ATM can cause multiple system dysfunctions and increase tumour susceptibility.21, 22, 23, 24 BMI‐1 is an acronym for B‐cell‐specific Moloney murine leukaemia virus integration site 1. The gene discussed is ATM; the disease is neoplasm.