GSDMB and asthma: In total, we identified 168,025 heterozygous KOs and 74,534 homozygous KOs for GSDMB. Under an additive model, GSDMB heterozygote KOs are predicted to have a decreased risk for asthma with OR = 0.90 (p = 5.9 × 10−50; 95% CI: 0.88–0.91).