Finally, we observed the predictive effect of c-Myc expression combined with TGF-β1 and ELF for outcomes in patients with HCC through analysis of the following eight groups: TGF-β1 high/ELF high/c-Myc high expression (ThEhMh), TGF-β1/ELF low/c-Myc high expression (ThElMh), TGF-β1 high/ELF high/c-Myc low expression (ThEhMl), TGF-β1 high/ELF low/c-Myc low expression (ThElMl), TGF-β1 low/ELF high/c-Myc high expression (TlEhMh), TGF-β1 low/ELF high/c-Myc low expression (TlEhMl), TGF-β1 low/ELF low/c-Myc high expression(TlElMh), TGF-β1 low/ELF low/c-Myc low expression (TlElMl). The gene discussed is MYC; the disease is hepatocellular carcinoma.