Immunohistochemical analysis of the epithelial marker E‐cadherin and the mesenchymal marker N‐cadherin in 30 PVTT and matched primary tumour tissues revealed that in PVTT tissues, the expression level of E‐cadherin was reduced, and the expression level of N‐cadherin was upregulated compared with that in tumour tissues (Fig. 1F). The gene discussed is CDH2; the disease is neoplasm.