For example, in The 2016 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia, AML with recurrent genetic abnormalities were classified into AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, AML with inv. The gene discussed is RUNX1; the disease is acute myeloid leukemia.