Cabozantinib is a tyrosine kinase inhibitor (TKI) targeting multiple receptor tyrosine kinases implicated in tumor angiogenesis, invasion, and metastasis, including MET (hepatocyte growth factor receptor), VEGFR2 (vascular endolethial growth factor receptor 2), AXL (GAS6 receptor), and RET (glial cell-derived neurotrophic factor receptor) [1]. The gene discussed is MET; the disease is neoplasm.