Among the 28 key candidate proteins, we also found 9 special proteins (DHX9, HNRNPR, RPL3, HNRNPA3, SF1, DDX5, EIF5B, BTF3, and RPL8) (Figure 4(c)), which were downregulated after TMZ treatment, and lower expression indicated worse prognosis of GBM patients (both OS and PFS) (Figure 5). The gene discussed is DHX9; the disease is glioblastoma.