The results showed that all of the cellular adhesion-related molecules, including immunoglobulin superfamily molecules (e.g., ICAM, VCAM), gap junction (GJ) molecule (e.g., connexin), tight junctions (TJs) molecule (e.g., occludin, ZO-1), and Ca2+ dependent cell adhesion molecule family (Cadherin) molecules (e.g., E-cadherin, cadherin4/18/5), were notably down-regulated in CV-A16 infection compared with EV-A71 infection (Figure 3). Here, TJP1 is linked to infection.