NOS3 and hydrops fetalis: We verified that the treatment for 6 months with atorvastatin alone or coupled with exercise in rats under ER regimen, after exclusive consumption of HF diet during 10 months, (HF/ER/S and HF/ER/S/Ex groups, respectively) resulted in an increment of eNOS expression, versus HF/ER (p = 0.016 and p = 0.006, respectively) or HF (p = 0.045 and p = 0.017, respectively) groups (Fig. 5b).