WNT5A and bacterial infectious disease: The first two panels (i and ii) of Figure 1A (peritonitis model), Figure 1B (airway infection model), and Figure 1C (polymicrobial sepsis model) demonstrate how pharmacological inhibition of Wnt5A secretion by IWP2 intensified bacterial infection, as evidenced by roughly 10-fold increased bacterial CFU harbored in harvested peritoneal cells and lung tissue homogenates.