TCF7L2 and Stroke: Research into how carriage of certain gene alleles, such as TCF7L2 or IL-6 can increase inflammation or stroke risk, respectively, and can be ameliorated by following a Mediterranean-type diet (42, 400, 401), or how gene splicing and features of senescence may be modulated by resveratrol in food (402), herald research into how gene, diet, and lifestyles can interact, with positive or negative effects on the immune system and health.