Activation of EGFR is known to be involved in many pathological processes such as endothelial dysfunction (Mehta et al., 2008), hypertension (Zhou et al., 2009), restenosis (Chan et al., 2003; Shafi et al., 2009), atherogenesis (Dreux et al., 2006), and cardiac remodeling (Iwamoto et al., 2003). This evidence concerns the gene EGFR and Hypertension.