As a part of the immune system, it maintains a predominant role in pathogen-induced bovine mastitis and mediates the innate and adaptive immune responses of the mammary gland by secreting proinflammatory cytokines and chemokines, including tumor necrosis factor- (TNF-) α, interleukin- (IL-) 1β, and IL-6, or promoting T and B lymphocyte responses [2–4]. The gene discussed is IL6; the disease is mastitis.