In line with these macroscopic results, the serum analysis also revealed liver injury and cholestasis, as shown by significantly increased levels of aspartate aminotransferase (AST), alanine aminotransferase, alkaline phosphatase, direct-bilirubin, indirect-bilirubin, and bile acid in a time-dependent manner (Supplementary Fig. S4a). Here, GPT is linked to cholestasis.