ESR1 and breast carcinoma: We found that higher expression of BARD1 was associated with decreased overall survival (OS) in ER-positive breast cancer patients from publicly available Curtis breast cancer data set22 published on oncomine platform (Fig. 1c) and in the meta-analysis of breast cancer patients from 27 data sets, many of which do not provide the details of ER positivity (Supplementary Fig. 2a).