Finally, combined Z-scores that were derived using diffusion from the more conservative RAD gene set yielded similar AD-related pathways such as Fx03 targets (FWER p = 0.064), antigen processing (FWER p = 0.02), and hippocampal development (FWER p = 0.065) (S4 Table). The gene discussed is RRAD; the disease is Alzheimer disease.