Consistent with proteomics, elevated expression of FMNL and NCL proteins and decreased expression of PRDX1 were identified in Group B compared to Group A. In addition, enhanced expression of FLNA, PHB2, and FABP5 was observed in Group C compared to Group A. In contrast with proteomics, we found that the expression of CLIC3 proteins were up‐regulated in tumor samples from patients with metastasis, while the transcripts were down‐regulated in metastasis (Fig. 2A and B). The gene discussed is CLIC3; the disease is neoplasm.