Protective effects of statins on diabetic cardiomyopathy have been reported to improve cardiovascular remodeling by suppression of arterial wall thickening and myocardial fibrosis, restoration of left ventricular diastolic function, preservation of angiotensin-converting enzyme-2 (ACE2), and reduction of oxidative stress [7–10]. This evidence concerns the gene ACE2 and diabetic cardiomyopathy.