Besides several studies demonstrating its ability to induce apoptosis (Hu et al., 2006; Li et al., 2009; Zhao et al., 2010), to arrest cell cycle (Yang et al., 2008) and suppress metastasis in many cancer cell types, it was reported that oroxylin A induces dissociation of HK2 from mitochoia in human breast carcinoma cell lines (Wei et al., 2013). Here, HK2 is linked to cancer.