VDAC1 and Alzheimer disease: The N-terminal domain of VDAC1, including the first 26 amino acid residues, is commonly considered the mobile part and an exposed moiety of the protein, putatively involved in the binding of cytosolic proteins in physiological conditions (Shi et al., 2003; Geula et al., 2012), as well as of Aβ peptide in AD (Thinnes, 2011).