Although we tried to assess correlations between C0 of bosutinib and the clinical/laboratory data (age, sex, CML phase, reason of taking bosutinib, body weight, white blood cell count, hemoglobin levels, platelet count, aspartate transaminase, alanine transaminase, serum albumin levels, total bilirubin, serum creatinine levels, lipase value), there were no independent factors of the clinical characteristics influencing C0 (data not shown). This evidence concerns the gene ALB and chronic myelogenous leukemia, BCR-ABL1 positive.