Amplicon libraries covering thirty commonly mutated genes implicated in myeloid malignancies, either covering the entire coding region (CALR, CEBPA, ETV6, EZH2, RUNX1, SH2B3, TET2, TP53, and ZRSR2) or mutational hotspots (ABL1, ASXL1, BRAF, CBL, CSF3R, DNMT3A, FLT3, GATA2, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NPM1, NRAS, PTPN11, SETBP1, SF3B1, SRSF2, and U2AF1), were generated. This evidence concerns the gene CBL and myeloid neoplasm.