A previous study has shown that a combination of the progestin medroxyprogesterone acetate (MPA) and the Ras inhibitor S-farnesylthiosalicylic acid (FTS, also known as Salirasib) inhibited tumor growth and enhanced type 2 EC cell death by reducing expression of ER-target genes, including TFF1 [32]. This evidence concerns the gene TFF1 and neoplasm.