In addition to such compounds that prevent androgen synthesis (i.e. abiraterone) or androgen receptor antagonists (i.e. Enzalutamid or Bicalutamid) [9], derivatives of androgen biosynthesis such as testosterone or 5α -dihydrotestosterone (5α -DHT) effectively reduce tumour growth in castration resistant VCaP cells [10]. Here, AR is linked to neoplasm.